PGRN Induces Impaired Insulin Sensitivity and Defective Autophagy in Hepatic Insulin Resistance

Progranulin (PGRN) has recently emerged as an important regulator for glucose metabolism and insulin sensitivity. However, the underlying mechanisms of PGRN in the regulation of insulin sensitivity and autophagy remain elusive. In this study, we aimed to address the direct effects of PGRN in vivo an...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Liu, Jiali, Li, Huixia, Zhou, Bo, Xu, Lin, Kang, Xiaomin, Yang, Wei, Wu, Shufang, Sun, Hongzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414747/
https://ncbi.nlm.nih.gov/pubmed/25664864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1266
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