Glycolipid Metabolism Disorder in the Liver of Obese Mice Is Improved by TUDCA via the Restoration of Defective Hepatic Autophagy

Objective. Tauroursodeoxycholic acid (TUDCA) has been considered an important regulator of energy metabolism in obesity. However, the mechanism underlying how TUDCA is involved in insulin resistance is not fully understood. We tested the effects of TUDCA on autophagic dysfunction in obese mice. Mate...

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Detalhes bibliográficos
Publicado no:Int J Endocrinol
Main Authors: Guo, Qinyue, Shi, Qindong, Li, Huixia, Liu, Jiali, Wu, Shufang, Sun, Hongzhi, Zhou, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668323/
https://ncbi.nlm.nih.gov/pubmed/26681941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/687938
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