Iron accelerates hemoglobin oxidation increasing mortality in vascular diseased guinea pigs following transfusion of stored blood

Non–transferrin-bound iron (NTBI) and free hemoglobin (Hb) accumulate in circulation following stored RBC transfusions. This study investigated transfusion, vascular disease, and mortality in guinea pigs after stored RBC transfusion alone and following cotransfusion with apo-transferrin (apo-Tf) and...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Baek, Jin Hyen, Yalamanoglu, Ayla, Gao, Yamei, Guenster, Ricardo, Spahn, Donat R., Schaer, Dominik J., Buehler, Paul W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414558/
https://ncbi.nlm.nih.gov/pubmed/28469086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93577
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