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Down Selection of Polymerized Bovine Hemoglobins for Use as Oxygen Releasing Therapeutics in a Guinea Pig Model

Hemoglobin (Hb)-based oxygen carriers (HBOCs) are being developed as resuscitative fluids for use in multiple medical applications and in lieu of blood transfusion. However, cardiovascular, central nervous system, and renal adverse events have largely impeded progress. This has prompted a need to ev...

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Detalhes bibliográficos
Main Authors: Baek, Jin Hyen, Zhou, Yipin, Harris, David R., Schaer, Dominik J., Palmer, Andre F., Buehler, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355313/
https://ncbi.nlm.nih.gov/pubmed/22416071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs109
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