A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination

Schwann cell (SC) myelination in the peripheral nervous system is essential for motor function, and uncontrolled SC proliferation occurs in cancer. Here, we show that a dual role for Hippo effectors TAZ and YAP in SC proliferation and myelination through modulating G-protein expression and interacti...

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Publicado en:Nat Commun
Main Authors: Deng, Yaqi, Wu, Lai Man Natalie, Bai, Shujun, Zhao, Chuntao, Wang, Haibo, Wang, Jincheng, Xu, Lingli, Sakabe, Masahide, Zhou, Wenhao, Xin, Mei, Lu, Q. Richard
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414202/
https://ncbi.nlm.nih.gov/pubmed/28443644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15161
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