A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination

Schwann cell (SC) myelination in the peripheral nervous system is essential for motor function, and uncontrolled SC proliferation occurs in cancer. Here, we show that a dual role for Hippo effectors TAZ and YAP in SC proliferation and myelination through modulating G-protein expression and interacti...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Deng, Yaqi, Wu, Lai Man Natalie, Bai, Shujun, Zhao, Chuntao, Wang, Haibo, Wang, Jincheng, Xu, Lingli, Sakabe, Masahide, Zhou, Wenhao, Xin, Mei, Lu, Q. Richard
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414202/
https://ncbi.nlm.nih.gov/pubmed/28443644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15161
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