YAP/TAZ initiate and maintain Schwann cell myelination

Nuclear exclusion of the transcriptional regulators and potent oncoproteins, YAP/TAZ, is considered necessary for adult tissue homeostasis. Here we show that nuclear YAP/TAZ are essential regulators of peripheral nerve development and myelin maintenance. To proliferate, developing Schwann cells (SCs...

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Udgivet i:eLife
Main Authors: Grove, Matthew, Kim, Hyukmin, Santerre, Maryline, Krupka, Alexander J, Han, Seung Baek, Zhai, Jinbin, Cho, Jennifer Y, Park, Raehee, Harris, Michele, Kim, Seonhee, Sawaya, Bassel E, Kang, Shin H, Barbe, Mary F, Cho, Seo-Hee, Lemay, Michel A, Son, Young-Jin
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287714/
https://ncbi.nlm.nih.gov/pubmed/28124973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20982
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