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Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury

Previously we showed that YAP/TAZ promote not only proliferation but also differentiation of immature Schwann cells (SCs), thereby forming and maintaining the myelin sheath around peripheral axons (Grove et al., 2017). Here we show that YAP/TAZ are required for mature SCs to restore peripheral myeli...

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Grove, Matthew, Lee, Hyunkyoung, Zhao, Huaqing, Son, Young-Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259960/
https://ncbi.nlm.nih.gov/pubmed/32436841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50138
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