Schwann cell proliferation during Wallerian degeneration is not necessary for regeneration and remyelination of the peripheral nerves: axon-dependent removal of newly generated Schwann cells by apoptosis

Peripheral nerve injury is followed by a wave of Schwann cell proliferation in the distal nerve stumps. To resolve the role of Schwann cell proliferation during functional recovery of the injured nerves, we used a mouse model in which injury-induced Schwann cell mitotic response is ablated via targe...

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Bibliographic Details
Main Authors: Yang, David P., Zhang, Dan P., Mak, Kimberley S., Bonder, Daniel E., Pomeroy, Scott L., Kim, Haesun A.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440648/
https://ncbi.nlm.nih.gov/pubmed/18374600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.01.017
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