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RNA activation‐independent DNA targeting of the Type III CRISPR‐Cas system by a Csm complex

The CRISPR‐Cas system is an adaptive and heritable immune response that destroys invading foreign nucleic acids. The effector complex of the Type III CRISPR‐Cas system targets RNA and DNA in a transcription‐coupled manner, but the exact mechanism of DNA targeting by this complex remains elusive. In...

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Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Park, Kwang‐Hyun, An, Yan, Jung, Tae‐Yang, Baek, In‐Young, Noh, Haemin, Ahn, Woo‐Chan, Hebert, Hans, Song, Ji‐Joon, Kim, Jeong‐Hoon, Oh, Byung‐Ha, Woo, Eui‐Jeon
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412804/
https://ncbi.nlm.nih.gov/pubmed/28364023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643700
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