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Different requirements of functional telomeres in neural stem cells and terminally differentiated neurons
Telomeres have been studied extensively in peripheral tissues, but their relevance in the nervous system remains poorly understood. Here, we examine the roles of telomeres at distinct stages of murine brain development by using lineage-specific genetic ablation of TRF2, an essential component of the...
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| 發表在: | Genes Dev |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5411705/ https://ncbi.nlm.nih.gov/pubmed/28428263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.295402.116 |
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