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Different requirements of functional telomeres in neural stem cells and terminally differentiated neurons

Telomeres have been studied extensively in peripheral tissues, but their relevance in the nervous system remains poorly understood. Here, we examine the roles of telomeres at distinct stages of murine brain development by using lineage-specific genetic ablation of TRF2, an essential component of the...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Lobanova, Anastasia, She, Robert, Pieraut, Simon, Clapp, Charlie, Maximov, Anton, Denchi, Eros Lazzerini
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411705/
https://ncbi.nlm.nih.gov/pubmed/28428263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.295402.116
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