Different requirements of functional telomeres in neural stem cells and terminally differentiated neurons

Telomeres have been studied extensively in peripheral tissues, but their relevance in the nervous system remains poorly understood. Here, we examine the roles of telomeres at distinct stages of murine brain development by using lineage-specific genetic ablation of TRF2, an essential component of the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Lobanova, Anastasia, She, Robert, Pieraut, Simon, Clapp, Charlie, Maximov, Anton, Denchi, Eros Lazzerini
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411705/
https://ncbi.nlm.nih.gov/pubmed/28428263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.295402.116
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