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Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres
Telomeres, the nucleoprotein complex at the ends of eukaryotic chromosomes, perform an essential cellular role in part by preventing the chromosomal end from initiating a DNA-damage response. This function of telomeres can be compromised as telomeres erode either as a consequence of cell division in...
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| Опубликовано в: : | Cold Spring Harb Perspect Med |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5411683/ https://ncbi.nlm.nih.gov/pubmed/28289249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026088 |
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