Dengue Virus NS2B/NS3 Protease Inhibitors Exploiting the Prime Side

The mosquito-transmitted dengue virus (DENV) infects millions of people in tropical and subtropical regions. Maturation of DENV particles requires proper cleavage of the viral polyprotein, including processing of 8 of the 13 substrate cleavage sites by dengue virus NS2B/NS3 protease. With no availab...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Lin, Kuan-Hung, Ali, Akbar, Rusere, Linah, Soumana, Djade I., Kurt Yilmaz, Nese, Schiffer, Celia A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411607/
https://ncbi.nlm.nih.gov/pubmed/28298600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00045-17
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