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Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects
Diabetes mellitus in early pregnancy increases the risk in infants of birth defects, such as neural tube defects (NTDs), known as diabetic embryopathy. NTDs are associated with hyperglycemia-induced protein misfolding and Caspase-8–induced programmed cell death. The present study shows that misfolde...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410824/ https://ncbi.nlm.nih.gov/pubmed/28396396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616119114 |
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