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Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects

Diabetes mellitus in early pregnancy increases the risk in infants of birth defects, such as neural tube defects (NTDs), known as diabetic embryopathy. NTDs are associated with hyperglycemia-induced protein misfolding and Caspase-8–induced programmed cell death. The present study shows that misfolde...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Zhao, Zhiyong, Cao, Lixue, Reece, E. Albert
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410824/
https://ncbi.nlm.nih.gov/pubmed/28396396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616119114
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