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Amelioration of intracellular stress and reduction of neural tube defects in embryos of diabetic mice by phytochemical quercetin
Diabetes mellitus in early pregnancy causes birth defects, including neural tube defects (NTDs). Hyperglycemia increases production of nitric oxide (NO) through NO synthase 2 (Nos2) and reactive oxygen species (ROS), generating nitrosative and oxidative stress conditions in the embryo. The present s...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4757833/ https://ncbi.nlm.nih.gov/pubmed/26887929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21491 |
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