Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus

Status epilepticus (SE), a medical emergency that is typically terminated through antiepileptic drug treatment, leads to hippocampus dysfunction typified by neurodegeneration, inflammation, altered neurogenesis, as well as cognitive and memory deficits. Here, we examined the effects of intranasal (I...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Long, Qianfa, Upadhya, Dinesh, Hattiangady, Bharathi, Kim, Dong-Ki, An, Su Yeon, Shuai, Bing, Prockop, Darwin J., Shetty, Ashok K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410779/
https://ncbi.nlm.nih.gov/pubmed/28396435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703920114
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