Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus

Status epilepticus (SE), a medical emergency that is typically terminated through antiepileptic drug treatment, leads to hippocampus dysfunction typified by neurodegeneration, inflammation, altered neurogenesis, as well as cognitive and memory deficits. Here, we examined the effects of intranasal (I...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Long, Qianfa, Upadhya, Dinesh, Hattiangady, Bharathi, Kim, Dong-Ki, An, Su Yeon, Shuai, Bing, Prockop, Darwin J., Shetty, Ashok K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2017
Aiheet:
PNAS Plus
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410779/
https://ncbi.nlm.nih.gov/pubmed/28396435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703920114
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