Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus

Status epilepticus (SE), a medical emergency that is typically terminated through antiepileptic drug treatment, leads to hippocampus dysfunction typified by neurodegeneration, inflammation, altered neurogenesis, as well as cognitive and memory deficits. Here, we examined the effects of intranasal (I...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Long, Qianfa, Upadhya, Dinesh, Hattiangady, Bharathi, Kim, Dong-Ki, An, Su Yeon, Shuai, Bing, Prockop, Darwin J., Shetty, Ashok K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410779/
https://ncbi.nlm.nih.gov/pubmed/28396435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703920114
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