TKI rotation-induced persistent deep molecular response in multi-resistant blast crisis of Ph+ CML

In chronic myeloid leukemia (CML) resistance against one or more BCR-ABL1 tyrosine kinase inhibitors (TKI) remains a clinical challenge. Preclinical data suggest that TKI combinations may overcome resistance. We report on a heavily pre-treated 78 year-old female patient with CML who developed multi-...

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Udgivet i:Oncotarget
Main Authors: Valent, Peter, Herndlhofer, Susanne, Schneeweiß, Mathias, Boidol, Bernd, Ringler, Anna, Kubicek, Stefan, Gleixner, Karoline V., Hoermann, Gregor, Hadzijusufovic, Emir, Müllauer, Leonhard, Sperr, Wolfgang R., Superti-Furga, Giulio, Mannhalter, Christine
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410285/
https://ncbi.nlm.nih.gov/pubmed/28416739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15481
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