Atrophin controls developmental signaling pathways via interactions with Trithorax-like

Mutations in human Atrophin1, a transcriptional corepressor, cause dentatorubral-pallidoluysian atrophy, a neurodegenerative disease. Drosophila Atrophin (Atro) mutants display many phenotypes, including neurodegeneration, segmentation, patterning and planar polarity defects. Despite Atro’s critical...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Yeung, Kelvin, Boija, Ann, Karlsson, Edvin, Holmqvist, Per-Henrik, Tsatskis, Yonit, Nisoli, Ilaria, Yap, Damian, Lorzadeh, Alireza, Moksa, Michelle, Hirst, Martin, Aparicio, Samuel, Fanto, Manolis, Stenberg, Per, Mannervik, Mattias, McNeill, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409829/
https://ncbi.nlm.nih.gov/pubmed/28327288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23084
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