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Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat
Large alterations in transcription accompany neurodegeneration in polyglutamine (polyQ) diseases. These pathologies manifest both general polyQ toxicity and mutant protein-specific effects. In this study, we report that the fat tumour suppressor gene mediates neurodegeneration induced by the polyQ p...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049215/ https://ncbi.nlm.nih.gov/pubmed/21278706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.1 |
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