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Glucocorticoid and cytokine crosstalk: Feedback, feedforward, and co-regulatory interactions determine repression or resistance

Inflammatory signals induce feedback and feedforward systems that provide temporal control. Although glucocorticoids can repress inflammatory gene expression, glucocorticoid receptor recruitment increases expression of negative feedback and feedforward regulators, including the phosphatase, DUSP1, t...

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Vydáno v:J Biol Chem
Hlavní autoři: Newton, Robert, Shah, Suharsh, Altonsy, Mohammed O., Gerber, Antony N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409484/
https://ncbi.nlm.nih.gov/pubmed/28283576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.777318
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