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Glucocorticoid and cytokine crosstalk: Feedback, feedforward, and co-regulatory interactions determine repression or resistance

Inflammatory signals induce feedback and feedforward systems that provide temporal control. Although glucocorticoids can repress inflammatory gene expression, glucocorticoid receptor recruitment increases expression of negative feedback and feedforward regulators, including the phosphatase, DUSP1, t...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Newton, Robert, Shah, Suharsh, Altonsy, Mohammed O., Gerber, Antony N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409484/
https://ncbi.nlm.nih.gov/pubmed/28283576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.777318
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