Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST

Samankaltaisia teoksia

• Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells
  Tekijä: Perkins, Emma M, et al.
  Julkaistu: (2018)
• Cerebellar ataxias: β‐III spectrin's interactions suggest common pathogenic pathways
  Tekijä: Perkins, Emma, et al.
  Julkaistu: (2016)
• β-III Spectrin Is Critical for Development of Purkinje Cell Dendritic Tree and Spine Morphogenesis
  Tekijä: Gao, Yuanzheng, et al.
  Julkaistu: (2011)
• β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations
  Tekijä: Clarkson, Yvonne L., et al.
  Julkaistu: (2014)
• Loss of β-III Spectrin Leads to Purkinje Cell Dysfunction Recapitulating the Behavior and Neuropathology of Spinocerebellar Ataxia Type 5 in Humans
  Tekijä: Perkins, Emma M., et al.
  Julkaistu: (2010)