Protein kinase CK2 modulates HSJ1 function through phosphorylation of the UIM2 domain

HSJ1 (DNAJB2), a member of the DNAJ family of molecular chaperones, is a key player in neuronal proteostasis maintenance. It binds ubiquitylated proteins through its Ubiquitin Interacting Motifs (UIMs) and facilitates their delivery to the proteasome for degradation. Mutations in the DNAJB2 gene lea...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Ottaviani, Daniele, Marin, Oriano, Arrigoni, Giorgio, Franchin, Cinzia, Vilardell, Jordi, Sandre, Michele, Li, Wenwen, Parfitt, David A., Pinna, Lorenzo A., Cheetham, Michael E., Ruzzene, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409130/
https://ncbi.nlm.nih.gov/pubmed/28031292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw420
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados