Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells

The PI3K/Akt pathway is interconnected to protein kinase CK2, which directly phosphorylates Akt1 at S129. We have previously found that, in HK-2 renal cells, downregulation of the CK2 regulatory subunit β (shCK2β cells) reduces S129 Akt phosphorylation. Here, we investigated in more details how the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Alcaraz, Estefania, Vilardell, Jordi, Borgo, Christian, Sarró, Eduard, Plana, Maria, Marin, Oriano, Pinna, Lorenzo A., Bayascas, José R., Meseguer, Anna, Salvi, Mauro, Itarte, Emilio, Ruzzene, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946142/
https://ncbi.nlm.nih.gov/pubmed/31910234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227340
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