Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

Background: Breast cancer patients with residual disease after neoadjuvant chemotherapy (NAC) have increased recurrence risk. Molecular characterization, knowledge of NAC response, and simultaneous generation of patient-derived xenografts (PDXs) may accelerate drug development. However, the feasibil...

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Udgivet i:J Natl Cancer Inst
Main Authors: Goetz, Matthew P., Kalari, Krishna R., Suman, Vera J., Moyer, Ann M., Yu, Jia, Visscher, Daniel W., Dockter, Travis J., Vedell, Peter T., Sinnwell, Jason P., Tang, Xiaojia, Thompson, Kevin J., McLaughlin, Sarah A., Moreno-Aspitia, Alvaro, Copland, John A, Northfelt, Donald W., Gray, Richard J., Hunt, Katie, Conners, Amy, Weinshilboum, Richard, Wang, Liewei, Boughey, Judy C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408989/
https://ncbi.nlm.nih.gov/pubmed/28376176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djw306
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