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Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

Background: Breast cancer patients with residual disease after neoadjuvant chemotherapy (NAC) have increased recurrence risk. Molecular characterization, knowledge of NAC response, and simultaneous generation of patient-derived xenografts (PDXs) may accelerate drug development. However, the feasibil...

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Publicado en:J Natl Cancer Inst
Main Authors: Goetz, Matthew P., Kalari, Krishna R., Suman, Vera J., Moyer, Ann M., Yu, Jia, Visscher, Daniel W., Dockter, Travis J., Vedell, Peter T., Sinnwell, Jason P., Tang, Xiaojia, Thompson, Kevin J., McLaughlin, Sarah A., Moreno-Aspitia, Alvaro, Copland, John A, Northfelt, Donald W., Gray, Richard J., Hunt, Katie, Conners, Amy, Weinshilboum, Richard, Wang, Liewei, Boughey, Judy C.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408989/
https://ncbi.nlm.nih.gov/pubmed/28376176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djw306
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