Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

Background: Breast cancer patients with residual disease after neoadjuvant chemotherapy (NAC) have increased recurrence risk. Molecular characterization, knowledge of NAC response, and simultaneous generation of patient-derived xenografts (PDXs) may accelerate drug development. However, the feasibil...

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Gepubliceerd in:J Natl Cancer Inst
Hoofdauteurs: Goetz, Matthew P., Kalari, Krishna R., Suman, Vera J., Moyer, Ann M., Yu, Jia, Visscher, Daniel W., Dockter, Travis J., Vedell, Peter T., Sinnwell, Jason P., Tang, Xiaojia, Thompson, Kevin J., McLaughlin, Sarah A., Moreno-Aspitia, Alvaro, Copland, John A, Northfelt, Donald W., Gray, Richard J., Hunt, Katie, Conners, Amy, Weinshilboum, Richard, Wang, Liewei, Boughey, Judy C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408989/
https://ncbi.nlm.nih.gov/pubmed/28376176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djw306
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