Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall

Patient-derived xenografts (PDX) are generated in immune deficient mice and demonstrate histologic and molecular features similar to their corresponding human tumors. However, murine tumors (non-human) spontaneously occur in these models. 120 consecutive patients with high-risk primary breast cancer...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Moyer, Ann M., Yu, Jia, Sinnwell, Jason P., Dockter, Travis J., Suman, Vera J., Weinshilboum, Richard M., Boughey, Judy C., Goetz, Matthew P., Visscher, Daniel W., Wang, Liewei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2019
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570466/
https://ncbi.nlm.nih.gov/pubmed/31231469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27001
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