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Structure of nascent chromatin is essential for hematopoietic lineage specification
The role of chromatin structure in lineage commitment of multipotent hematopoietic progenitors (HPCs) is presently unclear. We show here that CD34+ HPCs possess a post-replicative chromatin globally devoid of the repressive histone mark H3K27me3. This H3K27-unmodified chromatin is required for recru...
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| Veröffentlicht in: | Cell Rep |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408750/ https://ncbi.nlm.nih.gov/pubmed/28402853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.03.035 |
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