Delayed accumulation of H3K27me3 on nascent DNA is essential for recruitment of transcription factors at early stages of stem cell differentiation

Recruitment of transcription factors (TFs) to repressed genes in euchromatin is essential to activate new transcriptional programs during cell differentiation. However, recruitment of all TFs, including pioneer factors, is impeded by condensed H3K27me3-containing chromatin. Single-cell and gene-spec...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Petruk, Svetlana, Cai, Jingli, Sussman, Robyn, Sun, Guizhi, Kovermann, Sina K., Mariani, Samanta A., Calabretta, Bruno, McMahon, Steven B., Brock, Hugh W., Iacovitti, Lorraine, Mazo, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412717/
https://ncbi.nlm.nih.gov/pubmed/28410996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.03.006
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