Delayed accumulation of H3K27me3 on nascent DNA is essential for recruitment of transcription factors at early stages of stem cell differentiation

Recruitment of transcription factors (TFs) to repressed genes in euchromatin is essential to activate new transcriptional programs during cell differentiation. However, recruitment of all TFs, including pioneer factors, is impeded by condensed H3K27me3-containing chromatin. Single-cell and gene-spec...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Petruk, Svetlana, Cai, Jingli, Sussman, Robyn, Sun, Guizhi, Kovermann, Sina K., Mariani, Samanta A., Calabretta, Bruno, McMahon, Steven B., Brock, Hugh W., Iacovitti, Lorraine, Mazo, Alexander
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412717/
https://ncbi.nlm.nih.gov/pubmed/28410996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.03.006
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