Generation of Integration-free Induced Pluripotent Stem Cells from Human Peripheral Blood Mononuclear Cells Using Episomal Vectors

Induced Pluripotent Stem Cells (iPSCs) hold great promise for disease modeling and regenerative therapies. We previously reported the use of Episomal Vectors (EV) to generate integration-free iPSCs from peripheral blood mononuclear cells (PB MNCs). The episomal vectors used are DNA plasmids incorpor...

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Podrobná bibliografie
Vydáno v:J Vis Exp
Hlavní autoři: Wen, Wei, Zhang, Jian-Ping, Chen, Wanqiu, Arakaki, Cameron, Li, Xiaolan, Baylink, David, Botimer, Gary D., Xu, Jing, Yuan, Weiping, Cheng, Tao, Zhang, Xiao-Bing
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2017
Témata:
Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408725/
https://ncbi.nlm.nih.gov/pubmed/28117800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55091
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