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Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis

Characterization of molecular interactions in terms of basic binding parameters such as binding affinity, stoichiometry, and thermodynamics is an essential step in basic and applied science. MicroScale Thermophoresis (MST) is a sensitive biophysical method to obtain this important information. Relyi...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Entzian, Clemens, Schubert, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408713/
https://ncbi.nlm.nih.gov/pubmed/28117825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55070
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