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Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis

Characterization of molecular interactions in terms of basic binding parameters such as binding affinity, stoichiometry, and thermodynamics is an essential step in basic and applied science. MicroScale Thermophoresis (MST) is a sensitive biophysical method to obtain this important information. Relyi...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Entzian, Clemens, Schubert, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408713/
https://ncbi.nlm.nih.gov/pubmed/28117825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55070
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