Impaired lysosomal activity mediated autophagic flux disruption by graphite carbon nanofibers induce apoptosis in human lung epithelial cells through oxidative stress and energetic impairment

BACKGROUND: Graphite carbon nanofibers (GCNF) have emerged as a potential alternative of carbon nanotubes (CNT) for various biomedical applications due to their superior physico-chemical properties. Therefore in-depth understanding of the GCNF induced toxic effects and underlying mechanisms in biolo...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Mittal, Sandeep, Sharma, Pradeep Kumar, Tiwari, Ratnakar, Rayavarapu, Raja Gopal, Shankar, Jai, Chauhan, Lalit Kumar Singh, Pandey, Alok Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408471/
https://ncbi.nlm.nih.gov/pubmed/28454554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-017-0194-4
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