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Autophagic/lysosomal dysfunction in Alzheimer’s disease
Autophagy serves as the sole catabolic mechanism for degrading organelles and protein aggregates. Increasing evidence implicates autophagic dysfunction in Alzheimer’s disease (AD) and other neurodegenerative diseases associated with protein misprocessing and accumulation. Under physiologic condition...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979020/ https://ncbi.nlm.nih.gov/pubmed/24171818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt217 |
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