Runx1 Orchestrates Sphingolipid Metabolism and Glucocorticoid Resistance in Lymphomagenesis

The three‐membered RUNX gene family includes RUNX1, a major mutational target in human leukemias, and displays hallmarks of both tumor suppressors and oncogenes. In mouse models, the Runx genes appear to act as conditional oncogenes, as ectopic expression is growth suppressive in normal cells but dr...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Kilbey, A., Terry, A., Wotton, S., Borland, G., Zhang, Q., Mackay, N., McDonald, A., Bell, M., Wakelam, M.J.O., Cameron, E.R., Neil, J.C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408393/
https://ncbi.nlm.nih.gov/pubmed/27869314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25802
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