Runx1 Orchestrates Sphingolipid Metabolism and Glucocorticoid Resistance in Lymphomagenesis

The three‐membered RUNX gene family includes RUNX1, a major mutational target in human leukemias, and displays hallmarks of both tumor suppressors and oncogenes. In mouse models, the Runx genes appear to act as conditional oncogenes, as ectopic expression is growth suppressive in normal cells but dr...

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Bibliografiska uppgifter
I publikationen:J Cell Biochem
Huvudupphovsmän: Kilbey, A., Terry, A., Wotton, S., Borland, G., Zhang, Q., Mackay, N., McDonald, A., Bell, M., Wakelam, M.J.O., Cameron, E.R., Neil, J.C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408393/
https://ncbi.nlm.nih.gov/pubmed/27869314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25802
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