載入...
Computational Tool for Fast in silico Evaluation of hERG K(+) Channel Affinity
The development of a novel comprehensive approach for the prediction of hERG activity is herein presented. Software Phase has been used to derive a 3D-QSAR model, employing as alignment rule a common pharmacophore built on a subset of 22 highly active compounds (threshold Ki: 50 nM) against hERG K(+...
Na minha lista:
| 發表在: | Front Chem |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2017
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408157/ https://ncbi.nlm.nih.gov/pubmed/28503546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00007 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|