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A novel mechanism of immunity controls the onset of cinnamycin biosynthesis in Streptomyces cinnamoneus DSM 40646

Streptomyces cinnamoneus DSM 40646 produces the Class II lantibiotic cinnamycin which possesses an unusual mechanism of action, binding to the membrane lipid phosphatidylethanolamine (PE) to elicit its antimicrobial activity. A comprehensive analysis of the cinnamycin biosynthetic gene cluster has u...

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Pubblicato in:J Ind Microbiol Biotechnol
Autori principali: O’Rourke, Sean, Widdick, David, Bibb, Mervyn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408092/
https://ncbi.nlm.nih.gov/pubmed/27858169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-016-1869-9
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