Study of bicyclomycin biosynthesis in Streptomyces cinnamoneus by genetic and biochemical approaches

The 2,5-Diketopiperazines (DKPs) constitute a large family of natural products with important biological activities. Bicyclomycin is a clinically-relevant DKP antibiotic that is the first and only member in a class known to target the bacterial transcription termination factor Rho. It derives from c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Witwinowski, Jerzy, Moutiez, Mireille, Coupet, Matthieu, Correia, Isabelle, Belin, Pascal, Ruzzini, Antonio, Saulnier, Corinne, Caraty, Laëtitia, Favry, Emmanuel, Seguin, Jérôme, Lautru, Sylvie, Lequin, Olivier, Gondry, Muriel, Pernodet, Jean-Luc, Darbon, Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934819/
https://ncbi.nlm.nih.gov/pubmed/31882990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56747-7
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