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A novel mechanism of immunity controls the onset of cinnamycin biosynthesis in Streptomyces cinnamoneus DSM 40646

Streptomyces cinnamoneus DSM 40646 produces the Class II lantibiotic cinnamycin which possesses an unusual mechanism of action, binding to the membrane lipid phosphatidylethanolamine (PE) to elicit its antimicrobial activity. A comprehensive analysis of the cinnamycin biosynthetic gene cluster has u...

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Publicat a:J Ind Microbiol Biotechnol
Autors principals: O’Rourke, Sean, Widdick, David, Bibb, Mervyn
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408092/
https://ncbi.nlm.nih.gov/pubmed/27858169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-016-1869-9
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