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A novel mechanism of immunity controls the onset of cinnamycin biosynthesis in Streptomyces cinnamoneus DSM 40646

Streptomyces cinnamoneus DSM 40646 produces the Class II lantibiotic cinnamycin which possesses an unusual mechanism of action, binding to the membrane lipid phosphatidylethanolamine (PE) to elicit its antimicrobial activity. A comprehensive analysis of the cinnamycin biosynthetic gene cluster has u...

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Detalhes bibliográficos
Publicado no:J Ind Microbiol Biotechnol
Main Authors: O’Rourke, Sean, Widdick, David, Bibb, Mervyn
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408092/
https://ncbi.nlm.nih.gov/pubmed/27858169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-016-1869-9
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