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Targeting kinase signaling pathways with constrained peptide scaffolds

Kinases are amongst the largest families in the human proteome and serve as critical mediators of a myriad of cell signaling pathways. Since altered kinase activity is implicated in a variety of pathological diseases, kinases have become a prominent class of proteins for targeted inhibition. Althoug...

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Bibliografske podrobnosti
izdano v:Pharmacol Ther
Main Authors: Hanold, Laura E., Fulton, Melody D., Kennedy, Eileen J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407947/
https://ncbi.nlm.nih.gov/pubmed/28185915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.02.014
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