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Targeting kinase signaling pathways with constrained peptide scaffolds
Kinases are amongst the largest families in the human proteome and serve as critical mediators of a myriad of cell signaling pathways. Since altered kinase activity is implicated in a variety of pathological diseases, kinases have become a prominent class of proteins for targeted inhibition. Althoug...
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| 發表在: | Pharmacol Ther |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407947/ https://ncbi.nlm.nih.gov/pubmed/28185915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.02.014 |
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