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“Solvent hydrogen-bond occlusion”: a new model of polar desolvation for biomolecular energetics

Water engages in two important types of interactions near biomolecules: it forms ordered “cages” around exposed hydrophobic regions, and it participates in hydrogen bonds with surface polar groups. Both types of interaction are critical to biomolecular structure and function, but explicitly includin...

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Dades bibliogràfiques
Publicat a:J Comput Chem
Autors principals: Bazzoli, Andrea, Karanicolas, John
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407913/
https://ncbi.nlm.nih.gov/pubmed/28318014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.24740
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