Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy

Lowe syndrome and Dent disease are two conditions that result from mutations of the inositol 5-phosphatase oculocerebrorenal syndrome of Lowe (OCRL) and share the feature of impaired kidney proximal tubule function. Genetic ablation of Ocrl in mice failed to recapitulate the human phenotypes, possib...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Inoue, Kazunori, Balkin, Daniel M., Liu, Lijuan, Nandez, Ramiro, Wu, Yumei, Tian, Xuefei, Wang, Tong, Nussbaum, Robert, De Camilli, Pietro, Ishibe, Shuta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407733/
https://ncbi.nlm.nih.gov/pubmed/27895154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016080913
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados