A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells

Mutations in the inositol 5-phosphatase OCRL cause Lowe syndrome and Dent's disease. Although OCRL, a direct clathrin interactor, is recruited to late-stage clathrin-coated pits, clinical manifestations have been primarily attributed to intracellular sorting defects. Here we show that OCRL loss...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Nández, Ramiro, Balkin, Daniel M, Messa, Mirko, Liang, Liang, Paradise, Summer, Czapla, Heather, Hein, Marco Y, Duncan, James S, Mann, Matthias, De Camilli, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358339/
https://ncbi.nlm.nih.gov/pubmed/25107275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02975
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados