Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits

Epsin is an evolutionarily conserved endocytic clathrin adaptor whose most critical function(s) in clathrin coat dynamics remain(s) elusive. To elucidate such function(s), we generated embryonic fibroblasts from conditional epsin triple KO mice. Triple KO cells displayed a dramatic cell division def...

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Bibliographische Detailangaben
Hauptverfasser: Messa, Mirko, Fernández-Busnadiego, Rubén, Sun, Elizabeth Wen, Chen, Hong, Czapla, Heather, Wrasman, Kristie, Wu, Yumei, Ko, Genevieve, Ross, Theodora, Wendland, Beverly, De Camilli, Pietro
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2014
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161027/
https://ncbi.nlm.nih.gov/pubmed/25122462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03311
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