Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits

Epsin is an evolutionarily conserved endocytic clathrin adaptor whose most critical function(s) in clathrin coat dynamics remain(s) elusive. To elucidate such function(s), we generated embryonic fibroblasts from conditional epsin triple KO mice. Triple KO cells displayed a dramatic cell division def...

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Detalhes bibliográficos
Main Authors: Messa, Mirko, Fernández-Busnadiego, Rubén, Sun, Elizabeth Wen, Chen, Hong, Czapla, Heather, Wrasman, Kristie, Wu, Yumei, Ko, Genevieve, Ross, Theodora, Wendland, Beverly, De Camilli, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161027/
https://ncbi.nlm.nih.gov/pubmed/25122462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03311
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