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The association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrin
Monoubiquitination of plasma membrane proteins is a mechanism to control their endocytic trafficking by promoting their interaction with cytosolic adaptor proteins that contain ubiquitin (Ub)-binding domains. Epsin, which contains Ub interaction motifs (UIMs), as well as binding sites for the clathr...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549477/ https://ncbi.nlm.nih.gov/pubmed/15701696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409719102 |
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